Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Nafcillin
Antimicrobial Agents
Antibacterial Antibiotics
Penicillins
- Metabolism/Excretion
- Not dialyzable
- Plasma Protein Binding %
- 90
- Dose for Normal Renal Function
- 50-200 mg/kg/day q4-6h
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- 100%
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- Only adjust if hepatic and renal failure: 9-25 mg/kg dose q6h
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- Only adjust if hepatic and renal failure: 7.5-15 mg/kg dose q6h
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: Only adjust if hepatic and renal failure: 7.5-15 mg/kg dose q6h
- Supplement for Dialysis [Recommendation Level]: PD
- PD: Only adjust if hepatic and renal failure: 7.5-15 mg/kg dose q6h, or IP: no LD, maint 125 mg/L
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 100%, [B]
- References
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- Toxicity Notes
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