Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Hydralazine
Antihypertensive and Cardiovascular Agents
Antihypertensive Drugs
Vasodilators
- Metabolism/Excretion
- Acetylated in liver, 14% excreted unchanged in urine
- Plasma Protein Binding %
- 85-90
- Dose for Normal Renal Function
- Oral: 0.75-1 mg/kg/day q6-12h, max 200 mg/day; IV: 0.1-0.2 mg/kg dose q6h, max 20 mg dose
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- q8h
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- q8h
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- q12-24h
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: q12-24h
- Supplement for Dialysis [Recommendation Level]: PD
- PD: q12-24h
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: q8h, [D]
- References
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- Toxicity Notes
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