Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Propranolol
Antihypertensive and Cardiovascular Agents
Antihypertensive Drugs
Beta-Blockers
- Metabolism/Excretion
- Extensive liver metabolism; undergoes first-pass effect
- Plasma Protein Binding %
- 60-90
- Dose for Normal Renal Function
- Oral: 0.5-4 mg/kg/day q6-8h, max 16 mg/kg/day; IV: 0.01-0.1 mg/kg dose, up to 1 mg for infants, 3 mg for children
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- 100%
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- 100%
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- 100%
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: 100%
- Supplement for Dialysis [Recommendation Level]: PD
- PD: 100%
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 100%, not dialyzable, [D]
- References
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- Toxicity Notes
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