Dosing Guidlines for Children

Drug Detail for Pediatric Drugs


Esmolol

Antihypertensive and Cardiovascular Agents

Antihypertensive Drugs

Beta-Blockers


Metabolism/Excretion
69% excreted unchanged in urine
Plasma Protein Binding %
55
Dose for Normal Renal Function
0.5 mg/kg load, 50-300 µg/kg/min (doses up to 1000 µg/kg/min reported)
Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
100%
Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
100%
AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
100%
Supplement for Dialysis [Recommendation Level]: IHD
IHD: 100%
Supplement for Dialysis [Recommendation Level]: PD
PD: 100%
Supplement for Dialysis [Recommendation Level]: CRRT
CRRT: 100%, titrate to desired effect, [D]
References
Toxicity Notes