Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Fentanyl
Analgesics
Narcotics and Narcotic Antagonists
- Metabolism/Excretion
- Hepatic, minimal renal excretion
- Plasma Protein Binding %
- 80-85
- Dose for Normal Renal Function
- 0.5-2 µg/kg dose or 1-5 µg/kg/hr continuous
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- 75%
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- 75%
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- 50%
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: 50%
- Supplement for Dialysis [Recommendation Level]: PD
- PD: 50%
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 75%, titrate to effect, [B]
- References
- Hodges UM, Berg S, Naik SK, Bower S, Lloyd-Thomas A, Elliot M. Filtration of fentanyl is not the cause of the elevation of arterial blood pressure associated with post-bypass ultrafiltration in children. J Cardiothorac Vasc Anesth. 1994; 8: 653-7. [PMID: 7880994]
- Toxicity Notes
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