Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Mesna
Miscellaneous Agents
Antineoplastic Agents
Protective Agents
- Metabolism/Excretion
- Oxidized in blood, ~45% excreted in urine
- Plasma Protein Binding %
- 69-75
- Dose for Normal Renal Function
- Refer to individual protocols
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- 100%
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- 100%
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- 100%
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: 100%
- Supplement for Dialysis [Recommendation Level]: PD
- PD: 100%
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 100%, administer in an appropriate ratio to the amount of cyclphosphamide/ifosfamide given, [D]
- References
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- Toxicity Notes
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