Dosing Guidlines for Children
Drug Detail for Pediatric Drugs
Enalapril/Enalaprilat
Antihypertensive and Cardiovascular Agents
Antihypertensive Drugs
Angiotensin-Converting Enzyme (ACE) Inhibitors
- Metabolism/Excretion
- Hepatic, excreted in urine
- Plasma Protein Binding %
- 50-60
- Dose for Normal Renal Function
- Oral: 0.1 mg/kg dose q12h-24h; IV: 5-10 µg/kg dose q8-24h
- Adjustment for Renal Function GFR, mL/min/1.73m2 30-50
- 75%
- Adjustment for Renal Function GFR, mL/min/1.73m2 10-29
- 75%
- AdAdjustment for Renal Function GFR, mL/min/1.73m2 <10
- 50%
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: 50%
- Supplement for Dialysis [Recommendation Level]: PD
- PD: 50%
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 75%, [D]
- References
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- Toxicity Notes
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