Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Naloxone
Analgesics
Narcotics and Narcotic Antagonists
- General Toxicity Notes
-
- Excreted Unchanged %
- Hepatic
- Half-Life (NormalESRD) hours
- 1.0-1.5/No data
- Plasma Protein Binding %
- 54
- Volume of Distribution L/kg
- 3
- Dose for Normal Renal Function
- 2 mg IV
- Second Dose
-
- Adjustment for Renal Failure Method
- D
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 100% [D]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: Not applicable
- Supplement for Dialysis [Recommendation Level]: PD
- PD: Not applicable
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for GFR 10-50, [D]
- References
- Bowden CA, Krenzelok EP. Clinical applications of commonly used contemporary antidotes. A US perspective. Drug Saf. 1997; 16: 9-47. [PMID: 9010641] / Cherny NI. Opioid analgesics: comparative features and prescribing guidelines. Drugs. 1996; 51: 713-37. [PMID: 8861543]
- Toxicity Notes
-