Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Pindolol
Antihypertensive and Cardiovascular Agents
Antihypertensive Drugs
Beta-Blockers
- General Toxicity Notes
- Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
- Excreted Unchanged %
- 40
- Half-Life (NormalESRD) hours
- 2.5-4.0/3-4
- Plasma Protein Binding %
- 50
- Volume of Distribution L/kg
- 1.2
- Dose for Normal Renal Function
- 10-40 mg bid
- Second Dose
-
- Adjustment for Renal Failure Method
- D
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [A]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [A]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 100% [A]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: None
- Supplement for Dialysis [Recommendation Level]: PD
- PD: None
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for GFR 10-50,titrate, [D]
- References
- Ohnhaus EE, Heidemann H, Meier J, Maurer G. Metabolism of pindolol in patients with renal failure. Eur J Clin Pharmacol. 1982; 22: 423-8. [PMID: 7117354]
- Toxicity Notes
-