Dosing Guidlines for Adults

Drug Detail for Adult Drugs


Celiprolol

Antihypertensive and Cardiovascular Agents

Antihypertensive Drugs

Beta-Blockers


General Toxicity Notes
Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
Excreted Unchanged %
10
Half-Life (NormalESRD) hours
4-5/5
Plasma Protein Binding %
No data
Volume of Distribution L/kg
No data
Dose for Normal Renal Function
200 mg q24h
Second Dose
Adjustment for Renal Failure Method
D
Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
100% [D]
Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
100% [D]
Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
75% [D]
Supplement for Dialysis [Recommendation Level]: IHD
IHD: No data
Supplement for Dialysis [Recommendation Level]: PD
PD: None
Supplement for Dialysis [Recommendation Level]: CRRT
CRRT: Dose for GFR 10-50, titrate, [D]
References
Milne RJ, Buckley MM. Celiprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in cardiovascular disease. Drugs. 1991; 41: 941-69. [PMID: 1715268]
Toxicity Notes