Dosing Guidlines for Adults

Drug Detail for Adult Drugs


Carteolol

Antihypertensive and Cardiovascular Agents

Antihypertensive Drugs

Beta-Blockers


General Toxicity Notes
Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
Excreted Unchanged %
>50
Half-Life (NormalESRD) hours
7/33
Plasma Protein Binding %
20-30
Volume of Distribution L/kg
4.0
Dose for Normal Renal Function
0.5-10 mg q24h
Second Dose
Adjustment for Renal Failure Method
D
Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
100% [A]
Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
50% [A]
Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
25% [A]
Supplement for Dialysis [Recommendation Level]: IHD
IHD: No data
Supplement for Dialysis [Recommendation Level]: PD
PD: None
Supplement for Dialysis [Recommendation Level]: CRRT
CRRT: Dose for GFR 10-50,titrate, [D]
References
Amemiya M, Tabei K, Furuya H, Sakairi Y, Asano Y. Pharmacokinetics of carteolol in patients with impaired renal function. Eur J Clin Pharmacol. 1992; 43: 417-21. [PMID: 1451723] / Hasenfuss G, Sch&#246; fer-Korting M, Knauf H, Mutschler E, Just H. Pharmacokinetics of carteolol in relation to renal function. Eur J Clin Pharmacol. 1985; 29: 461-5. [PMID: 4092726]
Toxicity Notes