Dosing Guidlines for Adults

Drug Detail for Adult Drugs


Bopindolol

Antihypertensive and Cardiovascular Agents

Antihypertensive Drugs

Beta-Blockers


General Toxicity Notes
Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
Excreted Unchanged %
<10
Half-Life (NormalESRD) hours
4-10/Unchanged
Plasma Protein Binding %
No data
Volume of Distribution L/kg
2-3
Dose for Normal Renal Function
1-4 mg q24h
Second Dose
Adjustment for Renal Failure Method
D
Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
100% [D]
Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
100% [D]
Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
100% [D]
Supplement for Dialysis [Recommendation Level]: IHD
IHD: None
Supplement for Dialysis [Recommendation Level]: PD
PD: None
Supplement for Dialysis [Recommendation Level]: CRRT
CRRT: Dose for GFR 10-50,titrate, [D]
References
Harron DW, Goa KL, Langtry HD. Bopindolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1991; 41: 130-49. [PMID: 1706984]
Toxicity Notes