Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Betaxolol
Antihypertensive and Cardiovascular Agents
Antihypertensive Drugs
Beta-Blockers
- General Toxicity Notes
- Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
- Excreted Unchanged %
- 80-90
- Half-Life (NormalESRD) hours
- 15-20/30-35
- Plasma Protein Binding %
- 45-60
- Volume of Distribution L/kg
- 5-10
- Dose for Normal Renal Function
- 20 mg q24h
- Second Dose
-
- Adjustment for Renal Failure Method
- D
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 50% [D]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: None
- Supplement for Dialysis [Recommendation Level]: PD
- PD: None
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for GFR 10-50, titrate, [D]
- References
- Frishman WH, Tepper D, Lazar EJ, Behrman D. Betaxolol: a new long-acting beta 1-selective adrenergic blocker. J Clin Pharmacol. 1990; 30: 686-92. [PMID: 2205635]
- Toxicity Notes
-