Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Omeprazole
Miscellaneous Agents
Proton-Pump Inhibitors
- General Toxicity Notes
-
- Excreted Unchanged %
- Negligible
- Half-Life (NormalESRD) hours
- 0.5-1/Unchanged
- Plasma Protein Binding %
- 95
- Volume of Distribution L/kg
- No data
- Dose for Normal Renal Function
- 20-60 mg q24h
- Second Dose
-
- Adjustment for Renal Failure Method
- D
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [A]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [A]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 100% [A]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: None, [B]
- Supplement for Dialysis [Recommendation Level]: PD
- PD: None, [B]
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for GFR 10-50, [D]
- References
- Naesdal J, Andersson T, Bodemar G, Larsson R, Regå rdh CG, Skå nberg I, et al. Pharmacokinetics of [14C]omeprazole in patients with impaired renal function. Clin Pharmacol Ther. 1986; 40: 344-51. [PMID: 3742939]
- Toxicity Notes
-