Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Salmeterol
Miscellaneous Agents
Bronchodilators
- General Toxicity Notes
-
- Excreted Unchanged %
- <1
- Half-Life (NormalESRD) hours
- 5.5
- Plasma Protein Binding %
- 96
- Volume of Distribution L/kg
- No data
- Dose for Normal Renal Function
- 1-2 inhalations bid
- Second Dose
-
- Adjustment for Renal Failure Method
-
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [D]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 100% [D]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: None, [D]
- Supplement for Dialysis [Recommendation Level]: PD
- PD: None, [D]
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: 100%, [D]
- References
- Cazzola M, Testi R, Matera MG. Clinical pharmacokinetics of salmeterol. Clin Pharmacokinet. 2002; 41: 19-30. [PMID: 11825095]
- Toxicity Notes
- Because of the small therapeutic dose, systemic levels of salmeterol are low or undetectable after inhalation.