Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Methimazole
Miscellaneous Agents
Antithyroid Drugs
- General Toxicity Notes
-
- Excreted Unchanged %
- 7
- Half-Life (NormalESRD) hours
- 3-6/Unchanged
- Plasma Protein Binding %
- None
- Volume of Distribution L/kg
- 0.6
- Dose for Normal Renal Function
- 5-20 mg tid
- Second Dose
-
- Adjustment for Renal Failure Method
- D
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 100% [B]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 100% [B]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 100% [B]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: None, [D]
- Supplement for Dialysis [Recommendation Level]: PD
- PD: None, [D]
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for GFR 10-50, [D]
- References
- Jansson R, Lindströ m B, Dahlberg PA. Pharmacokinetic properties and bioavailability of methimazole. Clin Pharmacokinet. 1985; 10: 443-50. [PMID: 4042519]
- Toxicity Notes
-