Dosing Guidlines for Adults
Drug Detail for Adult Drugs
Gemifloxacin
Antimicrobial Agents
Antibacterial Antibiotics
Quinolone Antibiotics
- General Toxicity Notes
- Most agents in this group are malabsorbed in the presence of compounds that contain metals such as magnesium, calcium, aluminum, and iron. Poorly absorbed with antacids, sucralfate, and phosphate binders.
- Excreted Unchanged %
- 36±9.3
- Half-Life (NormalESRD) hours
- 4-12
- Plasma Protein Binding %
- 60-70
- Volume of Distribution L/kg
-
- Dose for Normal Renal Function
- 320 mg q24h
- Second Dose
-
- Adjustment for Renal Failure Method
-
- Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
- 320 mg q24h [D]
- Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
- 160 -320 mg q24h [D]
- Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
- 160 mg q24h [D]
- Supplement for Dialysis [Recommendation Level]: IHD
- IHD: Dose after dialysis
- Supplement for Dialysis [Recommendation Level]: PD
- PD: Dose for GFR <10
- Supplement for Dialysis [Recommendation Level]: CRRT
- CRRT: Dose for 30-50, [D]
- References
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- Toxicity Notes
-