Dosing Guidlines for Adults

Drug Detail for Adult Drugs


Penicillin VK

Antimicrobial Agents

Antibacterial Antibiotics

Penicillins


General Toxicity Notes
Excreted Unchanged %
26-65
Half-Life (NormalESRD) hours
0.6/4.1
Plasma Protein Binding %
75-89
Volume of Distribution L/kg
0.5
Dose for Normal Renal Function
125-500 mg q6-12h
Second Dose
Adjustment for Renal Failure Method
D
Adjustment for Renal Failure GFR, mL/min >50 [Recommended Level]
100%[D]
Adjustment for Renal Failure GFR, mL/min 10-50 [Recommended Level]
100%[D]
Adjustment for Renal Failure GFR, mL/min <10 [Recommended Level]
100%[D]
Supplement for Dialysis [Recommendation Level]: IHD
IHD: Dose after dialysis
Supplement for Dialysis [Recommendation Level]: PD
PD: Dose for GFR <10
Supplement for Dialysis [Recommendation Level]: CRRT
CRRT: Not applicable
References
Toxicity Notes